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Table 8 Comparison between proposed and reported methods of MZH and PYH

From: Simultaneous analysis of two drugs used as supportive treatment for COVID-19: comparative statistical studies and analytical ecological appraisal

Methods

Proposed method

Proposed method

Proposed method

Proposed method

Reported method [17]

Reported method [20]

Techniques

RSM

IDW

FSD

Direct at 290 nm

HPLC–UV

HPLC–UV

Linear range (µg/mL)

 MZH

5–50

5–50

5–50

 

203–304

160–410

 PYH

   

5–50

395–592

270–760

LOD (µg/mL)

 MZH

0.52

0.87

1.11

 

3.75

0.79

 PYH

   

0.43

1.90

3.48

Application

Navoproxin plus® tablets

Pyrimac® tablets

Vominore® tablets

Vomidoxine B6® tablets

Dizirest B6® tablets