Skip to main content

Table 4 Quantitative analysis of ASP and OMZ in Yosprala® tablets by the proposed methods and statistical comparison with the reported method [18]

From: Application of different quantitative analytical techniques for estimation of aspirin and omeprazole in pharmaceutical preparation

  %Recovery ± RSD
1DD TLC densitometry Reported methoda
ASP OMZ ASP OMZ ASP OMZ
Yosprala ® tabletsb 100.15 ± 0.621 99.62 ± 0.705 98.27 ± 0.523 99.18 ± 0.689 99.34 ± 0.945 100.01 ± 1.017
Standard additionc 98.77 ± 0.621 99.07 ± 0.821 99.25 ± 0.408 98.25 ± 0.258   
t-test (2.306)d 0.256 0.385 0.327 0.415   
F-test (6.388)d 1.294 1.186 1.257 1.824   
  1. aHPLC determination using C18 column and mobile phase consists of acetonitrile: water; pH 2.9 (60:40, by volume) with a flow rate of 1 mL/min and UV detection at 240 nm
  2. bAverage of five determinations
  3. cAverage of three determinations
  4. dThe values in parenthesis are tabulated values of “t” and “F” at (P = 0.05)