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Table 4 Quantitative analysis of ASP and OMZ in Yosprala® tablets by the proposed methods and statistical comparison with the reported method [18]

From: Application of different quantitative analytical techniques for estimation of aspirin and omeprazole in pharmaceutical preparation

 

%Recovery ± RSD

1DD

TLC densitometry

Reported methoda

ASP

OMZ

ASP

OMZ

ASP

OMZ

Yosprala ® tabletsb

100.15 ± 0.621

99.62 ± 0.705

98.27 ± 0.523

99.18 ± 0.689

99.34 ± 0.945

100.01 ± 1.017

Standard additionc

98.77 ± 0.621

99.07 ± 0.821

99.25 ± 0.408

98.25 ± 0.258

  

t-test (2.306)d

0.256

0.385

0.327

0.415

  

F-test (6.388)d

1.294

1.186

1.257

1.824

  
  1. aHPLC determination using C18 column and mobile phase consists of acetonitrile: water; pH 2.9 (60:40, by volume) with a flow rate of 1 mL/min and UV detection at 240 nm
  2. bAverage of five determinations
  3. cAverage of three determinations
  4. dThe values in parenthesis are tabulated values of “t” and “F” at (P = 0.05)
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BMC Chemistry

ISSN: 2661-801X

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