Table 3 SwissADME results of compounds derived from N-acylhydrazones
From: Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives
Compounds | MW < 500 | HA < 10 | HD < 5 | Log P < 5 | TPSA < 140 Å | Caco-2 (cm/s) | LR  < 9 | Log S > − 5 |
|---|---|---|---|---|---|---|---|---|
AH3 | 285.25 | 5 | 2 | 1.63 | 107.51 | 0.55 | 5 | − 3.61 |
AH4 | 256.26 | 4 | 3 | 1.18 | 81.92 | 0.55 | 4 | − 2.80 |
AH5 | 359.38 | 4 | 3 | 2.5 | 90.79 | 0.55 | 7 | − 4.18 |
Chloroquine | 305.85 | 2 | 1 | 3.68 | 28.16 | 0.56 | 8 | − 4.21 |
Artemether | 298.37 | 5 | 0 | 3.19 | 46.15 | 0.55 | 1 | − 3.85 |