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Table 1 Accuracy results

From: Development and validation of a HPLC-UV method for methadone hydrochloride quantification in a new oral solution with preservatives to be implemented in physicochemical stability studies

  Sample Concentration (mg/mL) Area Recovery percentaje
Intra-assay accuracy 1 7.5 2156.23 101.77%
2 2156.13 101.76%
3 2150.20 101.50%
4 10 2834.91 99.30%
5 2792.10 97.85%
6 2838.16 99.41%
7 2843.81 99.60%
8 2852.00 99.88%
9 2864.73 100.31%
10 12.5 3526.82 98.18%
11 3599.04 100.14%
12 3606.48 100.34%
    Median 100.00%
    %RSD 1.27%
Second-assay accuracy 1 7.5 2044.37 96.72%
2 2034.18 96.26%
3 2015.79 95.43%
4 10 2725.24 95.59%
5 2719.33 95.39%
6 2714.90 95.24%
7 2718.15 95.35%
8 2713.72 95.20%
9 2733.81 95.88%
10 12.5 3520.51 98.01%
11 3527.89 98.21%
12 3532.32 98.33%
    Median 96.30%
    %RSD 1.22%
  Inter-assay accuracy Median 98.15%
  %RSD 1.24%