A green TLC densitometric method for the simultaneous detection and quantification of naphazoline HCl, pheniramine maleate along with three official impurities

Table 4 Determination of NPZ, PHN in their dosage form and application of standard addition technique using the proposed TLC method

Naphcon-A^® eye drop	% found Mean^a ± SD	Standard addition technique
Naphcon-A^® eye drop	% found Mean^a ± SD	Taken	Added	Recovery %
NPZ	101.36 ± 1.51	10.0 µg band⁻¹	5.0 µg band⁻¹	101.30
			10.0 µg band⁻¹	101.75
			20.0 µg band⁻¹	99.99
Mean ± SD				101.01 ± 0.914
PHN	100.94 ± 1.73	20.0 µg band⁻¹	10.0 µg band⁻¹	100.95
			20.0 µg band⁻¹	99.02
			40.0 µg band⁻¹	100.84
Mean ± SD				100.27 ± 1.084

ISSN: 2661-801X