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Table 3 IC50 (μM) of some chosen synthesized compounds on colon carcinoma cells (HCT-116) and hepatocellular carcinoma cells lines (HepG-2)

From: Synthesis, screening as potential antitumor of new poly heterocyclic compounds based on pyrimidine-2-thiones

Compounds IC50 (μM)
HCT-116 HepG-2
4a 20.88 ± 1.88 35.22 ± 2.23
6a 31.92 ± 3.67 42.63 ± 4.09
7a 42.42 ± 5.54 59.07 ± 6.01
9a 38.32 ± 4.01 56.55 ± 5.23
10a 10.72 ± 0.83 18.95 ± 1.25
13a 54.01 ± 6.09 86.33 ± 7.33
14a 26.26 ± 3.09 37.87 ± 2.46
Vinblastine standard 3.61 ± 0.43 6.26 ± 0.69