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Table 1 Evaluation of cytotoxicity of some chosen synthesized compounds against colon carcinoma cells (HCT-116)

From: Synthesis, screening as potential antitumor of new poly heterocyclic compounds based on pyrimidine-2-thiones

Sample conc. (µg ml−1) Cell viability (%)
4a 6a 7a 9a 10a 13a 14a Vinblastine standard
50.000 16.38 26.18 29.78 32.08 14.27 35.18 21.73 12.98
25.000 19.51 37.22 41.05 43.03 17.01 44.91 27.15 16.08
12.500 27.13 46.34 50.68 52.76 23.99 54.45 37.72 20.74
6.250 48.44 70.17 74.29 77.85 44.13 59.90 52.89 39.34
3.125 58.63 85.23 83.55 85.49 52.47 88.11 63.31 48.60
1.560 75.93 91.02 94.47 96.11 66.74 98.22 80.84 59.31
0.000 (DMSO) 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00