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Fig. 2 | BMC Chemistry

Fig. 2

From: Synthesis, in vitro biological evaluation and molecular modelling of new 2-chloro-3-hydrazinopyrazine derivatives as potent acetylcholinesterase inhibitors‏ on PC12 cells

Fig. 2

IC50 (µM) values of synthesized compounds against AChE activity (IC50 = 0.53 µM). CHP4 > CHP5 > CHP3 > CHP1 > CHP2. The data are expressed in relation to AChE activity with respect to control as mean ± SD (n = 3, P < 0.001). Donepezil is used as a positive control

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BMC Chemistry

ISSN: 2661-801X

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