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Table 1 Physicochemical properties and chemical structures of the selected antibiotics commonly used on poultry production [29, 30]

From: Development and validation of liquid chromatography method for simultaneous determination of multiclass seven antibiotic residues in chicken tissues

Class Compound molecular formula and weight Chemical structure Solubility in water (mg/mL) Log Kow pKa
β-Lactams Amoxicillin, C16H19N3O5S, 365.4 g mol−1 3.4 0.87, 0.97 2.4, 2.8, 7.2
  Ampicillin, C16H19N3O4S, 349.4 g mol−1 10.1 1.45 2.53, 2.7 7.3
  Benzylpenicillin (penicillin G), C16H18N2O4S, 334.4 g mol−1 0.2 1.85 2.7, 2.8
Fluoro-quinolones Ciprofloxacin C17H18FN3O3, 331.3 g mol−1 36 0.4 3.01, 6.38, 8.70
Aminoglycoside Gentamicin C21H43N5O7, 477.6 g mol−1 100 -1.88 8.2
Macrolides Erythromycin C37H67NO13, 733.9 g mol−1 2 3.06, 2.48 8.88, 8.9
Sulfonamides Sulfamethoxazole C10H11N3O3S, 253.3 g mol−1 0.61 0.89, 0.48 1.85, 5.6
  1. Kow: the octanol–water partition coefficient
  2. pKa: acidity constant