Synthesis, in silico molecular docking analysis, pharmacokinetic properties and evaluation of antibacterial and antioxidant activities of fluoroquinolines

Table 6 Toxicity prediction of compounds computed by Pro-Tox II and OSIRIS property explorer

S. no	Formula	LD₅₀ (mg/kg)	Toxicity class	Organ toxicity
S. no	Formula	LD₅₀ (mg/kg)	Toxicity class	Hepatotoxicity	Carcinogenicity	Immunotoxicity	Mutagenicity	Cytotoxicity
4	C₁₀H₅ClFNO	2190	5	Inactive	Inactive	Inactive	Inactive	Inactive
5	C₁₁H₈FNO₂	1000	4	Active	Active	Active	Inactive	Inactive
6	C₁₂H₁₀FNO₂	800	4	Inactive	Active	Inactive	Inactive	Inactive
7	C₁₂H₆FNOS	80	3	Active	Inactive	Inactive	Inactive	Inactive
8	C₁₀H₅ClFNO₂	2190	5	Active	Inactive	Inactive	Inactive	Inactive
9	C₁₄H₁₆FN₃O₂	756	4	Inactive	Inactive	Active	Inactive	Active
10	C₂₂H₁₆FN₃	250	3	Active	Inactive	Inactive	Active	Inactive
15	C₁₁H₉NO₂	1000	4	Inactive	Active	Inactive	Inactive	Inactive
16	C₁₂H₁₁NO₃	800	4	Inactive	Active	Inactive	Inactive	Inactive
Vosaroxin	C₁₈H₁₉N₅O₄S	500	4	Active	Inactive	Inactive	Inactive	Inactive

ISSN: 2661-801X