Table 4 Drug-likeness predictions of compounds computed by SwissADME
S. no | Formula | Mol. wt. (g/mol) | NRB | NHA | NHD | TPSA (A°2) | LogP (cLogP) | Lipinski’s rule of five violation |
|---|---|---|---|---|---|---|---|---|
4 | C10H5ClFNO | 209.6 | 1 | 3 | 0 | 29.96 | 1.89 | 0 |
5 | C11H8FNO2 | 205.19 | 2 | 4 | 0 | 39.19 | 2.20 | 0 |
6 | C12H10FNO2 | 219.21 | 3 | 4 | 0 | 39.19 | 2.19 | 0 |
7 | C12H6FNOS | 231.25 | 2 | 3 | 0 | 66.16 | 2.10 | 0 |
8 | C10H5ClFNO2 | 225.60 | 1 | 4 | 1 | 50.19 | 1.67 | 0 |
9 | C14H16FN3O2 | 277.29 | 6 | 5 | 3 | 77.74 | 2.31 | 0 |
10 | C22H16FN3 | 341.38 | 4 | 3 | 1 | 37.28 | 3.47 | 0 |
15 | C11H9NO2 | 187.19 | 2 | 3 | 0 | 39.19 | 2.12 | 0 |
16 | C12H11NO3 | 217.22 | 3 | 4 | 0 | 48.42 | 2.52 | 0 |
Vosaroxin | C18H19N5O4S | 401.45 | 5 | 9 | 2 | 136.13 | 0.963 | 0 |