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Table 2 IC50 values of compounds 5a, 5r, and 5t for HCC cell lines (Huh7, HepG2, Mahlavu and SNU-475)

From: Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

IC50 values (µM)

Compound

Huh7

HepG2

Mahlavu

SNU475

5a

0.7 ± 0.1

3.1 ± 0.1

1.5 ± 0.4

1.4 ± 0.1

5r

4.1 ± 0.1

1.5 ± 0.9

19.7 ± 2.3

2.3 ± 1.7

5t

4.7 ± 0.9

3.8 ± 2.1

21.5 ± 5.9

8.5 ± 3.1

  1. Values are represented as mean ± SD from n = 3 replicates
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BMC Chemistry

ISSN: 2661-801X

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