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Table 2 Mean inhibition zone of the synthesized compounds in mm (mean ± SD) at different concentrations and their comparison with amoxicillin

From: Synthesis, antibacterial and antioxidant activities of Thiazole-based Schiff base derivatives: a combined experimental and computational study

Compounds

Conc. in μg/mL

Zone of inhibition (mm) mean ± SD

 

E. coli

P. aeruginosa

S. aureus

S. pyogenes

7

100

7.31 ± 0.03

8.00 ± 0.02

8.60 ± 0.02

7.95 ± 0.25

8

7.45 ± 0.02

7.95 ± 0.30

7.20 ± 0.04

7.25 ± 0.01

9

9.00 ± 0.01

10.00 ± 0.01

8.00 ± 0.04

8.67 ± 0.30

10

8.00 ± 0.02

7.00 ± 0.01

7.00 ± 0.00

7.95 ± 0.25

11

12.00 ± 0.01

12.43 ± 0.02

11.00 ± 0.00

13.00 ± 0.01

7

200

8.50 ± 0.01

9.80 ± 0.25

9.23 ± 0.02

10.03 ± 0.04

8

9.25 ± 0.04

9.00 ± 0.01

9.80 ± 0.45

8.67 ± 0.25

9

9.08 ± 0.01

9.43 ± 0.23

9.56 ± 0.25

9.89 ± 0.05

10

10.50 ± 0.02

12.00 ± 0.01

11.25 ± 0.15

11.67 ± 0.30

11

14.40 ± 0.04

13.00 ± 0.02

15.00 ± 0.01

14.45 ± 0.25

Amoxicillin

100

16.00 ± 0.00

16.00 ± 0.45

15.00 ± 0.01

16.00 ± 0.55

200

18.00 ± 0.01

8.50 ± 0.45

17.00 ± 0.04

18.00 ± 0.02