Inonotus obliquus polysaccharide ameliorates serum profiling in STZ-induced diabetic mice model

BMC Chemistry

Table 2 Significant metabolites between C and M group

No.	Rt/min	Ion mode	m/z	Formula	Metabolites	VIP	Fold change (M/C)	Related pathway
1	0.55	[M + H] +	90.05	C₃H₇NO₂	l-Alanine	1.62	0.56^#	Amino acid metabolism
2	0.55	[M + H]⁺	116.07	C₅H₉NO₂	l-Proline	1.77	0.57 ^#	Amino acid metabolism
3	0.55	[M + H]⁺	118.09	C₅H₁₁NO₂	l-Valine	1.93	0.71 ^#	Amino acid Metabolism
4	0.58	[M-H]⁻	167.02	C₅H₄N₄O₃	Uric acid	2.07	2.06 ^#	Purine metabolism
5	0.60	[M + H]⁺	132.10	C₆H₁₃NO₂	l-Leucine	3.62	0.49 ^#	Amino acid metabolism
6	0.66	[M + H]⁺	166.09	C₉H₁₁NO₂	l-Phenylalanine	1.59	0.54 ^#	Amino acid metabolism
7	2.78	[M + H]⁺	205.10	C₁₁H₁₂N₂O₂	l-Tryptophan	1.89	0.29 ^#	Amino acid metabolism
8	5.95	[M + H]⁺	318.30	C₁₈H₃₉NO₃	Phytosphingosine	2.00	0.60 *	Lipid metabolism
9	6.65	[M + H]⁺	302.31	C₁₈H₃₉NO₂	Sphinganine	1.18	0.67 ^#	Lipid metabolism
10	6.71	[M + H]⁺	494.32	C₂₄H₄₈NO₇P	LysoPC(16:1(9Z))	1.68	1.69 *	Lipid metabolism
11	6.90	[M + H]⁺	544.34	C₄₂H₈₀NO₈P	LysoPC(20:4(8Z,11Z,14Z,17Z))	3.77	0.59 ^#	Lipid metabolism
12	7.43	[M-H]⁻	319.23	C₂₀H₃₂O₃	12-HETE	3.89	15.36 ^#	Fatty acid metabolism
13	8.70	[M-H]⁻	303.23	C₂₀H₃₂O₂	Arachidonic acid	1.65	0.22 ^#	Fatty acid metabolism
14	9.32	[M + H]⁺	758.57	C₄₂H₈₀NO₈P	PC(20:1(11Z)/14:1(9Z))	8.72	0.42 *	Lipid metabolism
15	13.13	[M + H]⁺	815.70	C₄₇H₉₅N₂O₆P	SM(d18:0/24:1(15Z))	1.79	2.38 ^#	Lipid metabolism

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