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Table 4 Log CFU/ml values of the selected compound 1 in Aloe vera juice and White lotion USP

From: Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

Compound E. coli P. aeruginosa S. aureus C. albicans A. niger
Cfu/ml after days 14 days 28 days 14 days 28 days 14 days 28 days 14 days 28 days 14 days 28 days
Compound 1 # 2.75 ± 0.01a 2.21 ± 0.02b 2.51 ± 0.03c 2.21 ± 0.04d 2.22 ± 0.06e 2.62 ± 0.06f 2.11 ± 0.08 g 2.54 ± 0.02 h 2.50 ± 0.04i 2.80 ± 0.04j
@ 2.23 ± 0.01a 2.42 ± 0.03b 2.31 ± 0.04c 2.53 ± 0.03d 2.21 ± 0.04e 2.61 ± 0.03f 2.15 ± 0.06 g 2.06 ± 0.01 h 2.12 ± 0.02i 2.60 ± 0.02j
Sodium benzoate # 2.23 ± 0.01a 2.21 ± 0.01b 2.22 ± 0.01c 2.21 ± 0.02d 2.83 ± 0.01e 2.16 ± 0.01f 2.06 ± 0.02 g 2.80 ± 0.02 h 2.16 ± 0.02i 2.30 ± 0.01j
@ 3.23 ± 0.01a 3.33 ± 0.24b 3.22 ± 0.16c 3.21 ± 0.03d 3.83 ± 0.04e 3.16 ± 0.04f 3.07 ± 0.08 g 2.80 ± 0.08 h 3.16 ± 0.01i 3.32 ± 0.01j
Propyl paraben # 2.20 ± 0.01a 2.26 ± 0.06b 2.31 ± 0.01c 2.36 ± 0.02d 2.83 ± 0.02e 2.56 ± 0.01f 2.40 ± 0.01 g 2.50 ± 0.01 h 2.13 ± 0.05i 2.04 ± 0.02j
@ 3.20 ± 0.57a 3.24 ± 0.36b 3.31 ± 0.01c 3.30 ± 0.01d 3.83 ± 0.02e 3.56 ± 0.01f 3.90 ± 0.02 g 3.53 ± 0.01 h 3.13 ± 0.06i 3.43 ± 0.01j
Ethyl Paraben # 2.31 ± 0.03a 2.04 ± 0.18b 2.22 ± 0.16c 2.30 ± 0.11d 2.11 ± 0.04e 2.20 ± 0.01f 2.52 ± 0.02 g 2.20 ± 0.02 h 2.03 ± 0.02i 2.30 ± 0.05j
@ 3.36 ± 0.02a 3.00 ± 0.14b 3.24 ± 0.36c 3.34 ± 0.01d 3.16 ± 0.04e 3.10 ± 0.02f 3.50 ± 0.01 g 3.20 ± 0.01 h 3.03 ± 0.04i 3.30 ± 0.08j
  1. Initial microbial count present in inoculums 1 × 105–1 × 106; # Aloe vera juice; @ White lotion USP
  2. CFU = Colony forming unit, all experiments were conducted in triplicate (n = 3) and the mean values are presented. Different letters mean p < 0.05 in each line by One-way ANOVA test