Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

Table 1 Docking score, binding energy showed by aesculin derivatives in comparison to standard antimicrobials

Compound(s)	Structure	G-6-P synthase binding affinity
Compound(s)	Structure	Docking score	Energy (kJ/mol)
Compound 1		− 10.972	− 68.466
Compound 2		− 8.144	− 56.030
Aesculin		− 7.037	− 59.453
Standards	Ciprofloxacin	− 5.185	− 37.163
	Ampicillin	− 5.065	− 25.411
	Fluconazole	− 5.129	− 23.156

ISSN: 2661-801X