Ephedra alata fruit extracts: phytochemical screening, anti-proliferative activity and inhibition of DPPH, α-amylase, α-glucosidase, and lipase enzymes

Table 5 The IC₅₀ for different extracts fractions against DPPH, Lipase, α‑Amylase, and α-glucosidase in comparison of IC₅₀ of positive controls

	Target enzymes	Reference	Hexane fraction	Acetone fraction	Methanol fraction	Aqueous fraction
IC₅₀ (µg/mL)	DPPH	2.04 ± 0.74^a	44.05 ± 0.39	5.00 ± 0.51	1.70 ± 0.25	15.25 ± 0.30
	Lipase	12.3 ± 0.33^b	277.25 ± 0.79	77.56 ± 0.34	66.48 ± 0.50	274.407 ± 0.49
	α‑Amylase	28.84 ± 1.22^c	55.01 ± 1.23	189.94 ± 2.32	9.43 ± 0.6	16.37 ± 0.58
	α-Glucosidase	37.15 ± 0.33^C	167.68 ± 0.38	NI	46.16 ± 0.63	201.77 ± 0.48

^a Trolox, ^b Orlistat, ^c Acarbose, NI: no inhibition (inhibition at concentration higher than 400 µg/mL)

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