Table 1: ¹H & ¹³C-NMR spectroscopic data for cucurbitacins 1 and 2

1

5.95 (1H, brd s)

114.4

1

1.23 (1H, d, J = 4.4)

1.27 (1H, m)

36.1

2

144.6

2

4.43 (1H, dd, J = 6.0, 6.0)

71.5

3

198.5

3

212.8

4

47.6

4

50.3

5

136.9

5

140.5

6

5.79 (1H, m)

120.1

6

5.79 (1H, dd J = 2, 2)

119.8

7

2.07 (1H, m)

2.25 (1H, m)

50.2

7

2.43 (1H, brd s)

1.27 (1H, m)

24.3

8

2.29 (1H, m)

42.1

8

2.21 (1H, brd s)

42.9

9

50.3

9

45.0

10

49.8

10

2.79 (1H, d, J = 5.2)

33.9

11

215.9

11

215.9

12

2.07 (2H, m)

50.0

12

2.00 (1H, brd s)

2.07 (1H, brd s)

50.0

13

44.8

13

49.9

14

44.3

14

44.3

15

3.08 (1H, s)

2.39 (1H, s)

45.6

15

2.43 (1H, brd s)

3.17 (1H, s)

49.2

16

210.3

16

210.3

17

46.7

17

1.95 (1H, s)

2.53 (1H, s)

45.7

18

1.14 (3H, s)

19.1

18

1.23 (3H, s)

19.3

19

1.98 (1H, brd s)

2.54 (1H, brd s)

49.2

19

1.14 (3H, s)

20.0

20

1.38 (3H, s)

20.2

20

1.34 (3H, s)

21.2

21

3.92 (1H, brd s)

80.2

21

1.27 (3H, s)

29.2

22

210.0

22

1.00 s (3H, s)

24.3

23

2.47 (2H, brd s)

23.9

24

211.0

25

45.1

26

1.10 (3H, s)

20.0

27

1.03 (3H, s)

24.3

28

3.56 (3H, s)

34.8

29

1.26 (3H, s)

27.8

30

1.25 (3H, s)

20.1

1′

2.29 (1H, m)

43.3

2′

23.9

3′

24.2

4′

2.79 (1H, m)

36.3

5′

1.27 (3H, d, J = 5.2)

18.5

1″

44.2

2″

2.54 (1H, brd s)

1.98 (1H, d J = 3.2)

49.1

3″

2.02 (2H, m)

45.9

4″

5.97 (1H, m)

121.3

5″

138.3

6″

1.34 (3H s)

24.1

7″

0.81 (3H, s)

20.9

8″

1.00 (3H, s)

24.2