Table 1. Optimization of reaction temperature and time for compound 13 yield
From: The development of an effective synthetic route of rilpivirine
Time (°C) | Time/h | Yield % |
|---|---|---|
160 | 2 | 64 |
180 | 6 | 70 |
190 | 6 | 70.2 |
200 | 6 | 70.2 |
From: The development of an effective synthetic route of rilpivirine
Time (°C) | Time/h | Yield % |
|---|---|---|
160 | 2 | 64 |
180 | 6 | 70 |
190 | 6 | 70.2 |
200 | 6 | 70.2 |