Table 1. Optimization of reaction temperature and time for compound 13 yield
From: The development of an effective synthetic route of rilpivirine
| Time (°C) | Time/h | Yield % |
|---|---|---|
| 160 | 2 | 64 |
| 180 | 6 | 70 |
| 190 | 6 | 70.2 |
| 200 | 6 | 70.2 |
From: The development of an effective synthetic route of rilpivirine
| Time (°C) | Time/h | Yield % |
|---|---|---|
| 160 | 2 | 64 |
| 180 | 6 | 70 |
| 190 | 6 | 70.2 |
| 200 | 6 | 70.2 |