Table 6 Comparison of the urinary hormone profile using the 4-spot (DUTCH) or 24-h urine collection method (n = 26)
From: Reliability of a dried urine test for comprehensive assessment of urine hormones and metabolites
Variable | 24-h urine collection (ug/d) | 4-spot (ng/mg-Cr) | Z-score difference [95% CI]a | ICC [95% CI] |
|---|---|---|---|---|
Estrone | 13.69 (6.32, 19.16) | 14.37 (7.13, 18.75 | 0.00 [− 0.13, 0.13] | 0.95 [0.89, 0.97] |
Estradiol | 1.73 (0.80, 3.26) | 1.68 (0.92, 3.81) | 0.00 [− 0.16, 0.16] | 0.92 [0.83, 0.96] |
Estriol | 6.82 (3.57, 12.80) | 7.39 (4.15, 12.96) | 0.00 [− 0.24, 0.24] | 0.82 [0.64, 0.91] |
2-Hydroxyestrone | 3.33 (1.27, 6.24) | 3.72 (1.45, 6.75) | − 0.00 [− 0.09, 0.09] | 0.97 [0.94, 0.99] |
2-Hydroxyestradiol | 0.25 (0.11, 0.67) | 0.30 (0.13, 0.49) | − 0.00 [− 0.10, 0.10] | 0.97 [0.93, 0.99] |
4-Hydroxyestrone | 0.37 (0.19, 0.75) | 0.45 (0.27, 0.81) | − 0.00 [− 0.15, 0.15] | 0.93 [0.86, 0.97] |
16-Hydroxyestrone | 0.89 (0.42, 1.48) | 0.93 (0.57, 1.69) | 0.00 [− 0.19, 0.19] | 0.90 [0.77, 0.95] |
2-Methoxyestrone | 2.27 (1.30, 3.80) | 2.11 (1.54, 4.15) | 0.00 [− 0.19, 0.19] | 0.90 [0.78, 0.95] |
Testosterone | 9.15 (4.97, 51.92) | 9.33 (5.36, 54.73) | − 0.00 [− 0.10, 0.10] | 0.97 [0.93, 0.98] |
Epitestosterone | 7.23 (4.01, 11.23) | 7.53 (3.81, 13.90) | − 0.00 [− 0.07, 0.07] | 0.99 [0.97, 0.99] |
5a-Dihydrotestosterone | 5.53 (2.72, 11.59) | 6.40 (2.16, 11.91) | − 0.00 [− 0.09, 0.09] | 0.97 [0.94, 0.99] |
Androsterone | 1331.99 (854.41, 1940.29) | 1346.46 (818.59, 2065.66) | − 0.00 [− 0.09, 0.09] | 0.97 [0.94, 0.99] |
Etiocholanolone | 811.74 (463.17, 1045.23) | 797.60 (475.43, 1061.66) | − 0.00 [− 0.09, 0.09] | 0.98 [0.95, 0.99] |
5α-Androstanediol | 102.50 (54.83, 197.14) | 86.74 (51.31, 200.70) | − 0.00 [− 0.27, 0.27] | 0.78 [0.57, 0.89] |
5β-Androstanediol | 35.58 (14.05, 60.75) | 34.49 (13.91, 62.77) | 0.00 [− 0.22, 0.22] | 0.85 [0.70, 0.93] |
DHEA | 166.14 (80.45, 431.61) | 162.85 (78.17, 394.62) | − 0.00 [− 0.05, 0.05] | 0.99 [0.99, 1.00] |