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TableĀ 3 In silico ADMET profile of Piperine derivatives

From: Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies

Sr. no

Mol. wt

TPSA

No. of rotatable bonds

DonorHB

AccptHB

QPlogPo/w

QPlogBB

QPPMDCK

QPPCaco

5

372.21

47.57

4

1

4

4.34

0.134

4525.13

3140.96

7

343.38

47.57

4

1

4

4.549

0.429

1318.41

2476.54

9

277.32

48.01

3

0

6

2.15

0.118

2146.11

3887.00

11

356.46

44.77

6

0

3

5.445

0.229

2470.55

4427.72

13

362.33

74.98

5

0

6

2.955

0.939

408.022

836.747

15

373.36

74.21

6

0

5

3.846

0.945

484.356

980.622

17a

350.15

44.77

6

0

4

2.78

1.088

392.825

807.873

17b

352.34

71.08

8

0

7

2.18

1.874

234.985

708.548

17c

364.39

54.01

7

0

5

4.949

0.377

2442.11

4380.54