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Table 3 Total length of ISV of zebrafish in different treatment groups

From: Isolation and identification of alkaloids from Macleaya microcarpa by UHPLC–Q-TOF-MS and their cytotoxic activity in vitro, antiangiogenic activity in vivo

GroupTotal length of ISV (μm)P
Control (0.5% DMSO)3021.07 ± 359.8
Positive control (0.1 μg/mL PTK787)700.08 ± 214.2**0.006
Protopine (0.5 μg/mL)2946.44 ± 403.70.880
Protopine (1 μg/mL)2950.27 ± 378.90.881
Protopine (10 μg/mL)2818.69 ± 407.40.688
Chelerythrine (0.5 μg/mL)2952.11 ± 489.40.903
Chelerythrine (1 μg/mL)3065.54 ± 304.90.915
Chelerythrine (10 μg/mL)3091.49 ± 525.60.906
  1. **Comparison to control group P < 0.05