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Table 3 Total length of ISV of zebrafish in different treatment groups

From: Isolation and identification of alkaloids from Macleaya microcarpa by UHPLC–Q-TOF-MS and their cytotoxic activity in vitro, antiangiogenic activity in vivo

Group

Total length of ISV (μm)

P

Control (0.5% DMSO)

3021.07 ± 359.8

Positive control (0.1 μg/mL PTK787)

700.08 ± 214.2**

0.006

Protopine (0.5 μg/mL)

2946.44 ± 403.7

0.880

Protopine (1 μg/mL)

2950.27 ± 378.9

0.881

Protopine (10 μg/mL)

2818.69 ± 407.4

0.688

Chelerythrine (0.5 μg/mL)

2952.11 ± 489.4

0.903

Chelerythrine (1 μg/mL)

3065.54 ± 304.9

0.915

Chelerythrine (10 μg/mL)

3091.49 ± 525.6

0.906

  1. **Comparison to control group P < 0.05