From: Synthesis and therapeutic potential of imidazole containing compounds
Compounds | Antibacterial activity (MIC in (µg/mL) | |||
---|---|---|---|---|
Gram negative bacteria | Gram positive bacteria | |||
E. coli | P. aeruginosa | B. subtilis | S. aureus | |
4a | 125.0 | 125.0 | 125.0 | 125.0 |
4b | 125.0 | 125.0 | 125.0 | 125.0 |
4c | 125.0 | 125.0 | 125.0 | 125.0 |
4d | 125.0 | 125.0 | 125.0 | 125.0 |
4e | 125.0 | 125.0 | 125.0 | 125.0 |
4f | 125.0 | 125.0 | 125.0 | 125.0 |
4g | 125.0 | 125.0 | 125.0 | 125.0 |
4h | 125.0 | 125.0 | 31.0 | 63.0 |
4i | 125.0 | 125.0 | 125.0 | 125.0 |
4j | 125.0 | 125.0 | 125.0 | 125.0 |
4k | 125.0 | 125.0 | 125.0 | 125.0 |
4l | 125.0 | 125.0 | 125.0 | 125.0 |
4m | 125.0 | 125.0 | 125.0 | 125.0 |
4n | 125.0 | 63.0 | 125.0 | 125.0 |
Amikacin sulphate | 2.44 | 9.77 | 9.77 | 9.77 |
Ampicillin | 100 | 100 | – | 250 |
Chloramphenicol | 50 | 50 | – | 50 |