Table 31. Antitubercular activity of the synthesized compounds (73a-j) Makwane et al. [49]
From: Synthesis and therapeutic potential of imidazole containing compounds
Compounds | Ar1 | Antitubercular activity inhibition (%) (ppm) M. tuberculosis H37Rv strain | Antitubercular activity MIC* (μg/mL) M. tuberculosis H37Rv strain | |
|---|---|---|---|---|
25 | 50 | |||
73a | C6H5 | 22 | 45 | 12 |
73b | 2-ClC6H4 | 32 | 79 | 7.5 |
73c | 3-ClC6H4 | 36 | 80 | 6.5 |
73d | 4-ClC6H4 | 32 | 78 | 7 |
73e | 2-BrC6H4 | 29 | 73 | 10 |
73f | 3-BrC6H4 | 30 | 76 | 8.5 |
73g | 4-BrC6H4 | 30 | 75 | 9 |
73h | 2-NO2C6H4 | 28 | 82 | 5.5 |
73i | 3- NO2C6H4 | 27 | 84 | 4 |
73j | 4-NO2C6H4 | 32 | 83 | 5 |