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Table 21 Antioxidant activity of the synthesized derivatives (61a-j) Naureen et al. [41]

From: Synthesis and therapeutic potential of imidazole containing compounds

Compounds

R1

R2

R3

Antioxidant activity

Inhibition (%) at 0.5 mM

IC50 (µM)

61a

H

Cl

CH3

62.58 ± 0.7

175.26 ± 1.24

61b

H

Cl

Br

71.74 ± 0.2

146.27 ± 1.09

61c

Br

H

F

71.87 ± 0.5

181.26 ± 1.1

61d

H

Br

CH3

90.39 ± 0.5

148.26 ± 1.2

61e

H

Br

Cl

20.97 ± 0.5

–

61f

H

CH3

H

67.61 ± 0.3

162.27 ± 1.2

61g

H

CH3

CH3

44.21 ± 0.7

–

61h

H

CH3

Br

7.11 ± 0. 2

–

61i

H

CH3

F

18.91 ± 0. 6

–

61j

H

CH3

OCH3

23.03 ± 0.5

–

Thiourea

   

–

–

Quercetin

   

93.21 ± 0.9

16.96 ± 0.1