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Table 20 Antitumor activity of the synthesized derivatives (60a-j) Sharma et al. [40]

From: Synthesis and therapeutic potential of imidazole containing compounds

Compounds

Substituent R

Substituent R’

DLA cells CTC50 μg/mL

EAC cells CTC50 μg/mL

60a

190.26

60.50

60b

114.00

240.00

60c

98.56

31.25

60d

309.67

200.22

60e

 > 500

489.34

60f

207.60

115.31

60

238.50

31.25

60 h

 > 500

 > 500

60i

405.68

305.91

60j

150.26

94.63

  1. CTCs The cytotoxic concentration (which inhibited 50% of total cells)