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Table 14 IC50 values of the synthesized compounds (20a-j) against C6 and HepG2 cancer cell line Yurttas et al. [35]

From: Synthesis and therapeutic potential of imidazole containing compounds

Compounds

IC50 value

C6

HepG2

20a

27.0 ± 1.41

50.0 ± 5.0

20b

20 ± 2.0

26.33 ± 1.53

20c

32.67 ± 6.43

275.0 ± 35.36

20d

22.0 ± 3.61

29.33 ± 1.15

20e

16.33 ± 2.31

31.67 ± 7.23

20f

19.50 ± 2.12

28.67 ± 1.15

20g

15.67 ± 2.52

58.33 ± 2.89

20h

 > 500

 > 500

20i

24.33 ± 4.04

 > 500

20j

19.33 ± 2.31

 > 500

Cisplatin

23.0 ± 1.73

46.67 ± 7.64