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Table 2 In vitro cytotoxic activity of extracts of S. macrosiphon on cancerous cell lines (A549, MCF-7, MDA-MB-231)

From: Phytochemical constituents and biological activities of Salvia macrosiphon Boiss.

Fractions IC50 (µg/mL)
A549 MCF-7 MDA-MB-231 HDF
n-Hexane 20.89 ± 0.35 10.24 ± 0.15 20.98 ± 0.25 26.90 ± 1.24
Chloroform 22.87 ± 2.56 11.72 ± 1.56 25.67 ± 2.78 113.50 ± 5.24
Ethyl acetate 169.80 ± 3.56 76.43 ± 2.78 157.00 ± 6.78 189.50 ± 7.24
Methanol 344.96 ± 8.78 805.34 ± 10.45 589.00 ± 10.67 > 800
Etoposide 16.58 ± 0.78 22.08 ± 0.39 20.30 ± 0.21 92.70 ± 1.20