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Table 3 MIC, MBC and dehydrogenase activity (MTT test) of total phenolics in different solvent extracts of S. scardica and P. major

From: Extracts of medicinal plants with natural deep eutectic solvents: enhanced antimicrobial activity and low genotoxicity

Sample/indicator XXGly/Sa XXGly/Pb CAPD/Sa CAPD/Pb 70% EtOH/S 70% EtOH/P
S. pyogenes SAIM 10535
 MIC (µg/ml) 380 NAc 0.19 NA > 67.5 > 69.3
 DEHA (%) – NA 39.88 ± 9.6 NA – –
 MBC (µg/ml) 380 NA 1.56 NA > 67.5 > 69.3
E. coli ATCC 35218
 MIC (µg/ml) 47.5 38.75 0.39 3.984 > 67.5 > 69.3
 DEHA (%) – – 1.31 ± 0.87 – – –
 MBC (µg/ml) 47.5 38.75 0.78 3.984 > 67.5 > 69.3
S. aureus ATCC 29213
 MIC (µg/ml) NA NA 0.098 1.99 > 67.5 > 69.3
 DEHA (%) NA NA 9.8 ± 2.3 – – –
 MBC (µg/ml) NA NA 0.39 1.99 > 67.5 > 69.3
P. aeruginosa ATCC 27853
 MIC (µg/ml) 23.75 19.37 NA NA > 67.5 > 69.3
 DEHA (%) – – NA NA – –
 MBC (µg/ml) 23.75 19.37 NA NA > 67.5 > 69.3
C. albicans SAIM 562
 MIC (µg/ml) 23.75 19.37 0.19 1.99 > 67.5 > 69.3
 DEHA (%) – – 7.595 ± 2.1 – – –
 MBC (µg/ml) 23.75 19.37 0.78 1.99 > 67.5 > 69.3
B. cereus ATCC 9634
 MIC (µg/ml) 23.75 38.75 NA NA > 67.5 > 69.3
 DEHA (%) 50 ± 12.3 – NA NA – –
 MBC (µg/ml) 47.5 38.75 NA NA > 67.5 > 69.3
  1. Extracts with XXPD and XXGlH are inactive against all tested microorganisms
  2. aExtract of S. scardica
  3. bExtract of P. major
  4. cNA: no activity. DEHA data are expressed as the mean ± SD of three measurements
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BMC Chemistry

ISSN: 2661-801X

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