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Table 3 MIC, MBC and dehydrogenase activity (MTT test) of total phenolics in different solvent extracts of S. scardica and P. major

From: Extracts of medicinal plants with natural deep eutectic solvents: enhanced antimicrobial activity and low genotoxicity

Sample/indicator

XXGly/Sa

XXGly/Pb

CAPD/Sa

CAPD/Pb

70% EtOH/S

70% EtOH/P

S. pyogenes SAIM 10535

 MIC (µg/ml)

380

NAc

0.19

NA

> 67.5

> 69.3

 DEHA (%)

NA

39.88 ± 9.6

NA

 MBC (µg/ml)

380

NA

1.56

NA

> 67.5

> 69.3

E. coli ATCC 35218

 MIC (µg/ml)

47.5

38.75

0.39

3.984

> 67.5

> 69.3

 DEHA (%)

1.31 ± 0.87

 MBC (µg/ml)

47.5

38.75

0.78

3.984

> 67.5

> 69.3

S. aureus ATCC 29213

 MIC (µg/ml)

NA

NA

0.098

1.99

> 67.5

> 69.3

 DEHA (%)

NA

NA

9.8 ± 2.3

 MBC (µg/ml)

NA

NA

0.39

1.99

> 67.5

> 69.3

P. aeruginosa ATCC 27853

 MIC (µg/ml)

23.75

19.37

NA

NA

> 67.5

> 69.3

 DEHA (%)

NA

NA

 MBC (µg/ml)

23.75

19.37

NA

NA

> 67.5

> 69.3

C. albicans SAIM 562

 MIC (µg/ml)

23.75

19.37

0.19

1.99

> 67.5

> 69.3

 DEHA (%)

7.595 ± 2.1

 MBC (µg/ml)

23.75

19.37

0.78

1.99

> 67.5

> 69.3

B. cereus ATCC 9634

 MIC (µg/ml)

23.75

38.75

NA

NA

> 67.5

> 69.3

 DEHA (%)

50 ± 12.3

NA

NA

 MBC (µg/ml)

47.5

38.75

NA

NA

> 67.5

> 69.3

  1. Extracts with XXPD and XXGlH are inactive against all tested microorganisms
  2. aExtract of S. scardica
  3. bExtract of P. major
  4. cNA: no activity. DEHA data are expressed as the mean ± SD of three measurements