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Table 2 Antibacterial activity of the target compounds 5a5z against Xoo and Xoc

From: Design, synthesis, and biological activity of novel 1,2,4-oxadiazole derivatives

Compounds Xoo Xoc
50 µg/mL (%) EC50 (µg/mL) 50 µg/mL (%) EC50 (µg/mL)
5a 13.50 ± 3.33 NT 17.20 ± 1.60 NT
5b 0 NT 0 NT
5c 29.00 ± 3.90 NT 20.40 ± 1.00 NT
5d 0 NT 0 NT
5e 0 NT 0 NT
5f 6.70 ± 4.30 NT 12.60 ± 1.10 NT
5 g 0 NT 0 NT
5 h 10.10 ± 3.20 NT 11.30 ± 5.30 NT
5i 10.90 ± 1.00 NT 19.40 ± 2.10 NT
5j 42.17 ± 1.39 74.70 ± 5.46 41.37 ± 5.42 88.47 ± 4.21
5 k 30.59 ± 3.19 85.30 ± 3.66 15.58 ± 2.84 199.65 ± 18.98
5 l 14.16 ± 2.93 129.15 ± 11.16 29.95 ± 3.57 172.18 ± 13.94
5 m 65.85 ± 3.32 36.25 ± 1.77 33.01 ± 3.23 76.35 ± 4.82
5n 42.77 ± 2.13 56.75 ± 5.98 53.73 ± 3.24 50.93 ± 8.07
5o 26.94 ± 0.65 122.80 ± 7.32 31.60 ± 5.28 108.27 ± 5.99
5p 11.99 ± 1.18 225.35 ± 8.03 64.53 ± 3.42 31.40 ± 2.07
5q 43.78 ± 2.02 63.32 ± 1.58 33.61 ± 4.13 123.34 ± 8.55
5r 71.89 ± 1.56 24.14 ± 2.72 48.53 ± 1.66 51.11 ± 3.05
5 s 26.30 ± 2.37 95.12 ± 14.87 30.28 ± 2.88 116.76 ± 13.97
5t 38.16 ± 2.27 102.45 ± 5.99 50.37 ± 3.23 56.50 ± 6.26
5u 64.97 ± 3.46 28.82 ± 2.25 65.10 ± 4.12 19.04 ± 2.13
5v 85.37 ± 1.46 19.44 ± 2.22 64.59 ± 4.43 21.78 ± 2.82
5w 40.60 ± 3.95 75.61 ± 2.21 40.12 ± 3.23 75.22 ± 3.93
5x 61.97 ± 0.92 25.37 ± 6.98 40.29 ± 3.84 101.96 ± 5.81
5y 78.44 ± 5.54 28.52 ± 3.14 20.63 ± 6.75 125.57 ± 15.77
5z 44.07 ± 2.36 66.51 ± 5.53 53.70 ± 3.73 55.32 ± 2.96
BMT 35.12 ± 2.72 77.46 ± 6.15 45.56 ± 5.76 68.50 ± 7.87
TDC 25.12 ± 3.31 99.31 ± 7.59 37.58 ± 2.84 91.05 ± 8.84
  1. Average of three replicates
  2. NT not tested