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Table 1 Nematocidal and antifungal activity of compounds 5a5z

From: Design, synthesis, and biological activity of novel 1,2,4-oxadiazole derivatives

Compounds M. incognita R. solani
Corrected mortality rate (%)a、 Inhibition rate (%)b
5a 33.4 ± 2.7 28.7 ± 1.3
5b 28.9 ± 5.2 15.6 ± 0.7
5c 37.6 ± 8.1 25.2 ± 2.2
5d 26.6 ± 2.0 20.4 ± 1.2
5e 0 18.8 ± 1.7
5f 29.5 ± 2.7 34.6 ± 2.3
5 g 31.3 ± 5.3 16.1 ± 1.1
5 h 29.4 ± 6.1 19.1 ± 0.5
5i 40.3 ± 1.8 23.5 ± 1.6
5j 39.7 ± 4.2 15.0 ± 2.3
5 k 14.7 ± 27 34.7 ± 0.8
5 l 31.3 ± 3.8 22.1 ± 0.8
5 m 48.0 ± 3.7 23.8 ± 3.2
5n 63.3 ± 7.7 29.4 ± 1.0
5o 35.5 ± 2.4 47.0 ± 1.7
5p 25.3 ± 3.7 10.4 ± 0.6
5q 44.8 ± 6.7 26.1 ± 0.8
5r 36.7 ± 5.0 29.1 ± 0.5
5 s 27.3 ± 8.8 13.3 ± 1.6
5t 35.6 ± 3.4 25.8 ± 1.3
5u 40.8 ± 3.4 34.5 ± 2.3
5v 55.0 ± 7.7 34.3 ± 0.3
5w 26.6 ± 4.0 32.9 ± 1.1
5x 47.3 ± 3.8 13.6 ± 3.2
5y 34.6 ± 2.4 39.4 ± 1.4
5z 36.5 ± 2.6 27.8 ± 1.6
Tioxazafen 29.0 ± 4.5 NT
Fluopicolide 100 NT
Azoxystrobin NT 100
  1. Average of three replicates
  2. NT not tested
  3. a Target compounds 5a-5z at a concentration of 100 μg/mL against J2 of M. incognita
  4. b Target compounds 5a-5z at a concentration of 50 μg/mL against R.solani