Skip to main content

Table 5 Minimum inhibitory concentration (MIC) of titled compounds [49]

From: Therapeutic potential of oxadiazole or furadiazole containing compounds

Compound   S. aureus B. subtilis P. aeruginosa E. coli C. albicans
R X ATCC 25923 ATCC 6633 ATCC 27853 ATCC 27853 ATCC 10231
6a C6H5 O 0.3 0.15 0.15 1.25 2.5
6b 2-CH3 C6H5 O 0.31 0.07 1.25 0.625 5.0
6c 3-CH3 C6H5 O 0.625 0.15 5.0 2.5 10
6d 4-CH3 C6H5 O 2.5 2.5 0.03 5.0 1.25
6e 2-Cl C6H5 O 0.15 1.25 0.019 0.019 5.0
6f 3-Cl C6H5 O 0.15 0.625 1.25 1.25 2.5
6g 4-Cl C6H5 O 0.15 0.3 0.019 0.07 0.15
6h 3-NO2 C6H5 O - 10 1.25
6i 4-NO2 C6H5 O 2.5 0.625 5.0 10
7a 2-CH3 C6H5 S 1.25 2.5 10
7b 4-CH3 C6H5 S 1.25 5.0 2.5 1.25 5.0
7c 3-OH C6H5 S 2.5 1.25 0.019 2.5 10
7d 4-OH C6H5 S 0.15 0.625 2.5 0.625 1.25
7e 4-Cl C6H5 S 0.625 0.07 5.0 0.03 0.31
7f 3-NO2 C6H5 S 2.5 2.5 10 1.25 2.5
7g 4-NO2 C6H5 S 2.5 5.0 5.0 0.1 0.15
Ampicillin    0.019 0.005 0.005 0.01
Fluconazole    0.01