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Table 21 Anti-TMV activities of titled compounds at 500 μg/mL in vivo [1]

From: Therapeutic potential of oxadiazole or furadiazole containing compounds

Compounds Rate (%) Compounds Rate (%)
Curative activity Protective activity Curative activity Protective activity
40 38.5 ± 1.2 35.2 ± 3.1 448 60.0 ± 5.6 36.4 ± 1.0
41 36.9 ± 5.1 14.4 ± 2.9 449 26.9 ± 2.9 43.3 ± 3.0
42 26.8 ± 5.2 54.5 ± 2.9 4410 48.7 ± 5.1 25.2 ± 2.9
43a 22.3 ± 6.4 54.6 ± 5.2 4415 51.9 ± 3.0 45.6 ± 4.2
43b 47.2 ± 2.8 38.8 ± 4.5 40’ 41.8 ± 1.0 41.7 ± 1.7
43c 44.8 ± 9.5 36.8 ± 0.8 41’ 17.5 ± 1.2 32.2 ± 1.6
444 7.1 ± 1.7 51.2 ± 7.6 42’ 17.7 ± 1.2 42.6 ± 2.2
445 37.4 ± 3.5 27.8 ± 5.5 432 49.3 ± 2.0 19.6 ± 2.4
446 50.6 ± 4.7 42.9 ± 2.5 4410 33.9 ± 1.3 20.2 ± 1.0
447 37.1 ± 3.3 23.5 ± 1.1 4415 35.3 ± 2.3 19.3 ± 0.8
NNM 54.2 ± 2.9 65.7 ± 2.2