From: Therapeutic potential of oxadiazole or furadiazole containing compounds
Compounds | Rate (%) | Compounds | Rate (%) | ||
---|---|---|---|---|---|
Curative activity | Protective activity | Curative activity | Protective activity | ||
40 | 38.5 ± 1.2 | 35.2 ± 3.1 | 448 | 60.0 ± 5.6 | 36.4 ± 1.0 |
41 | 36.9 ± 5.1 | 14.4 ± 2.9 | 449 | 26.9 ± 2.9 | 43.3 ± 3.0 |
42 | 26.8 ± 5.2 | 54.5 ± 2.9 | 4410 | 48.7 ± 5.1 | 25.2 ± 2.9 |
43a | 22.3 ± 6.4 | 54.6 ± 5.2 | 4415 | 51.9 ± 3.0 | 45.6 ± 4.2 |
43b | 47.2 ± 2.8 | 38.8 ± 4.5 | 40’ | 41.8 ± 1.0 | 41.7 ± 1.7 |
43c | 44.8 ± 9.5 | 36.8 ± 0.8 | 41’ | 17.5 ± 1.2 | 32.2 ± 1.6 |
444 | 7.1 ± 1.7 | 51.2 ± 7.6 | 42’ | 17.7 ± 1.2 | 42.6 ± 2.2 |
445 | 37.4 ± 3.5 | 27.8 ± 5.5 | 432’ | 49.3 ± 2.0 | 19.6 ± 2.4 |
446 | 50.6 ± 4.7 | 42.9 ± 2.5 | 4410’ | 33.9 ± 1.3 | 20.2 ± 1.0 |
447 | 37.1 ± 3.3 | 23.5 ± 1.1 | 4415’ | 35.3 ± 2.3 | 19.3 ± 0.8 |
NNM | 54.2 ± 2.9 | 65.7 ± 2.2 |  |  |  |