Table 2 Antimicrobial activity of titled compounds (2a-h) and (3a-h) [41]
From: Therapeutic potential of oxadiazole or furadiazole containing compounds
Compound | Diameter of zone of inhibition (mm) | |||||
|---|---|---|---|---|---|---|
Antibacterial activity | Antifungal activity | |||||
S. aureus | B. subtilis | E. coli | P. aeruginosa | C. albicans | A. niger | |
2a | 14 | 21 | 10 | 17 | 09 | 10 |
2b | 18 | 19 | 12 | 15 | 10 | 11 |
2c | 30 | 27 | 14 | 18 | 09 | 11 |
2d | 19 | 22 | 11 | 18 | 10 | 11 |
2e | 28 | 28 | 14 | 14 | 10 | 09 |
2f | 14 | 19 | 10 | 15 | 10 | 10 |
2g | 21 | 23 | 13 | 19 | 11 | 09 |
2h | 14 | 20 | 10 | 16 | 09 | 10 |
3a | 11 | 12 | 10 | 09 | 11 | 11 |
3b | 10 | 12 | 09 | 11 | 12 | 12 |
3c | 20 | 21 | 12 | 13 | 11 | 11 |
3d | 20 | 22 | 16 | 18 | 10 | 11 |
3e | 18 | 19 | 11 | 13 | 11 | 10 |
3f | 11 | 13 | 10 | 11 | 10 | 11 |
3g | 12 | 14 | 09 | 12 | 10 | 10 |
3h | 10 | 13 | 09 | 11 | 10 | 11 |
Ciprofloxacin | 26 | 26 | 28 | 25 | – | – |
Fluconazole | – | – | – | – | 26 | 25 |