Table 5 Urease inhibitory screening results of the synthesized compounds (T1–T20)
Compounds | % inhibition | IC50 (µg/ml) | |||
|---|---|---|---|---|---|
25 (µg/ml) | 50 (µg/ml) | 75 (µg/ml) | 100 (µg/ml) | ||
T1 | 25.76 | 47.98 | 72.9 | 91.99 | 51.70 |
T2 | 40.45 | 49.54 | 55.67 | 67.57 | 53.04 |
T3 | 28.19 | 50.00 | 65.89 | 79.12 | 54.01 |
T4 | 35.45 | 49.45 | 63.67 | 79.45 | 50.52 |
T5 | 23.34 | 44.35 | 70.87 | 90.87 | 54.46 |
T6 | 38.45 | 50.34 | 65.61 | 80.89 | 47.02 |
T7 | 23.98 | 46.89 | 76.09 | 91.90 | 52.07 |
T8 | 22.45 | 39.58 | 68.58 | 92.67 | 56.43 |
T9 | 33.45 | 53.67 | 70.46 | 92.67 | 46.34 |
T10 | 27.90 | 46.89 | 70.90 | 89.80 | 51.90 |
T11 | 25.00 | 42.45 | 68.88 | 92.67 | 54.59 |
T12 | 43.56 | 46.57 | 52.56 | 61.56 | 58.06 |
T13 | 26.57 | 48.78 | 73.98 | 98.89 | 50.05 |
T14 | 41.70 | 46.23 | 50.49 | 57.78 | 67.02 |
T15 | 29.03 | 37.14 | 61.78 | 73.12 | 61.04 |
T16 | 45.76 | 49.10 | 53.87 | 59.12 | 52.85 |
T17 | 37.91 | 42.38 | 57.61 | 71.42 | 57.47 |
T18 | 40.90 | 46.79 | 55.89 | 67.9 | 54.30 |
T19 | 31.89 | 47.98 | 52.98 | 65.87 | 63.24 |
T20 | 28.98 | 49.09 | 69.09 | 81.90 | 52.34 |
Thiourea | 29.98 | 46.76 | 67.78 | 76.78 | 54.25 |