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Table 4 Antioxidant screening results of the synthesized compounds (T1–T20)

From: Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents

Compounds

% inhibition

IC50 (µg/ml)

25 (µg/ml)

50 (µg/ml)

75 (µg/ml)

100 (µg/ml)

T1

25.45

49.65

69.67

94.78

46.83

T2

45.67

56.98

70.16

84.21

34.83

T3

43.56

60.12

75.67

88.98

34.38

T4

38.45

58.34

88.61

98.89

37.50

T5

42.34

55.67

68.98

78.12

39.13

T6

31.67

53.67

77.78

92.67

45.66

T7

46.75

52.56

60.56

70.41

38.54

T8

43.91

58.67

67.54

82.57

36.12

T9

40.56

60.67

83.61

92.16

35.42

T10

45.56

51.56

57.57

62.67

43.57

T11

35.78

52.89

70.89

89.9

45.36

T12

44.45

51.45

68.56

70.61

39.56

T13

43.46

57.67

73.76

89.56

36.40

T14

37.56

60.68

85.79

95.61

37.52

T15

38.56

50.64

62.16

80.56

47.99

T16

43.65

51.45

67.26

81.76

41.30

T17

48.75

62.57

78.16

84.61

24.90

T18

39.59

68.57

80.13

95.89

33.34

T19

38.45

58.34

80.61

96.89

38.99

T20

33.45

53.67

70.46

92.67

46.34

Ascorbic acid

38.67

63.68

84.78

94.45

35.44

  1. Italics signifies the most active compound in comparison to the standard compound
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BMC Chemistry

ISSN: 2661-801X

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