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Table 4 Determination of FEX and MON in pharmaceutical preparations using the proposed method and reference methods

From: New pencil graphite electrodes for potentiometric determination of fexofenadine hydrochloride and montelukast sodium in their pure, synthetic mixtures, and combined dosage form

Commercial Name

Composition

Amount found, mga

R% ± SD

t-valueb

F-valuec

Sensor 1 FEX.Mol

 Fexofenadine

Fexofenadine 120 mg

119.37

99.47 ± 1.16

1.06

3.53

 Azmalir

Montelukast 10 mg

–

–

–

–

 Combination form

Fexofenadine 120 mg

119.27

99.39 ± 0.87

1.96

3.39

Montelukast 10 mg

–

–

–

–

Sensor 2 MON.Co

 Fexofenadine

Fexofenadine 120 mg

–

–

–

–

 Azmalir

Montelukast 10 mg

10.05

100.5 ± 1.74

4.07

1.66

 Combination form

Fexofenadine 120 mg

–

–

–

–

Montelukast 10 mg

9.97

99.71 ± 1.61

2.82

3.20

Sensor 3 FEX.MOl + MON.Co

 Fexofenadine

Fexofenadine 120 mg

119.53

100.39 ± 0.78

2.26

3.46

 Azmalir

Montelukast 10 mg

10.12

98.80 ± 1.20

2.77

1.77

 Combination form

Fexofenadine 120 mg

120.83

100.69 ± 0.69

2.13

2.95

Montelukast 10 mg

9.89

98.88 ± 1.34

2.22

3.30

  1. aAverage of 3 replicates
  2. bt critical 4.302 (0.05)
  3. cf critical 19 (0.05), n = 3