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Table 1 Parameters for deposition of PLA/paclitaxel mixed layer film by spin coating and nanofibers by electrospinning

From: Fabrication of polylactic acid/paclitaxel nano fibers by electrospinning for cancer therapeutics

Process parameters for PLA/paclitaxel films by spin coating
Speed (rpm) 3000
Operational temperature (°C) Room temperature
Deposition time (min) 4
PLA concentration in TFA (wt.%) 40
Paclitaxel concentration in DMSO 2.5 mg/100 μl (50%), 5 mg/100 μl (100%)
Process parameters for PLA/paclitaxel nanofibers by electrospinning
Voltage (kV) 17
Flow rate (μl/min) 1 × 10−2
Syringe outer/inner diameter (mm) 5.0 × 10−1/2.6 × 10−1
Operational temperature (°C) Room temperature
Working distance (cm) 14 or 15
Deposition time (s) > 60
PLA concentration in TFA (wt.%) 40
Paclitaxel concentration in DMSO 2.5 mg/1 ml (50%), 5 mg/1 ml (100%)
Volumetric mixing ratio (PLA: Paclitaxel) 3 ml: 200 μl