Table 1 Antibacterial activiy (mean IZ diameter (mm) ± SD) of metalloporphyrins, corresponding ligands, metal salts, and gentamycin with concentration 500 mg/L
From: Antibacterial activity of Cu(II) and Co(II) porphyrins: role of ligand modification
Compounds | Antibacterial activiy (mean IZ diameter (mm) ± SD) | |||
|---|---|---|---|---|
S. aureus | S. pyogenes | E. coli | K. pneumonia | |
CoTPPCOOH | 16.5 ± 0.5 | 15 ± 0.3 | 16 ± 0.5 | 16 ± 0.6 |
CoTPPOMe | 12 ± 0.2 | 14 ± 0.6 | 10 ± 0.3 | 12 ± 02 |
CuTPPCOOMe | 16 ± 0.2 | 15 ± 0.5 | 13 ± 0.6 | 13.5 ± 075 |
CuTPPNH2 | 13 ± 0.4 | 13.5 ± 0.3 | 12 ± 0.45 | 12.5 ± 0.6 |
H2TPPCOOH | 8.5 ± 0.2 | 9 ± 0.3 | 7.5 ± 0. 3 | 7.5 ± 0.4 |
H2TPPCOOMe | 8.25 ± 0.3 | 8 ± 0.2 | 7.5 ± 0.03 | 7.5 ± 0.2 |
H2TPPOMe | 7 ± 0.3 | 7.25 ± 0.3 | 7 ± 0.3 | 7 ± 0.2 |
H2TPPNH2 | 7.5 ± 0.2 | 7.75 ± 0.3 | 7 ± 0.01 | 7 ± 0.2 |
CuCl2·2H2O | 6.75 ± 0.2 | 7 ± 0.3 | 6.25 ± 0.02 | 6.5 ± 0.4 |
Co acetate | 6.5 ± 0.1 | 7 ± 0.2 | 6.5 ± 0.1 | 6.5 ± 0.2 |
DMSO | 0 ± 0.00 | 0 ± 0.00 | 0 ± 0.00 | 0 ± 0.00 |
10 µg gentamicin | 25 ± 0.6 | 27 ± 0.75 | 26 ± 0.75 | 25 ± 0.5 |