Fig. 2
From: Structural basis of the anti-ageing effects of polyphenolics: mitigation of oxidative stress
Resveratrol and stilbenoid derivatives. Groups 1–4 reflect the primary research paper(s) in which the series shown was first described (1a–1l = ref [25]; 2a–2f = ref [28]; 3a–3i = ref [29]; 4a–4m = Refs. [34, 35]). Where given in the literature, efficacy in antioxidant/radical quenching assays is shown. (Note resveratrol was studied in all four groups and is shown as entries 1a, 2a, 3b and 4g for comparison). In vitro activity data—DMPO EC50 concentration giving 50% of max effect in DMPO superoxide radical scavenging assay. TEMP-1O2—singlet oxygen quenching. DPPH -DPPH nitrogen radical scavenging assay. General schemes or scaffolds are enclosed in dotted lines