Table 1 Antimicrobial activity of the newly synthesized thiazolidinone derivatives 5a–n against the multidrug resistant tested microbial strains
Comp. | Gram (+ve) bacteria | Gram (−ve) bacteria | Fungi | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
S. aureus | MRSA | S. pneumoniae | E. coli | K. pneumoniae | P. aeruginosa | A. baumannii | A. flavus | A. niger | C. albicans | |
5a | 3 | – | – | – | – | – | – | – | – | – |
5b | 4 | – | – | – | – | – | – | – | – | – |
5c | 3 | – | – | – | – | – | – | – | – | – |
5d | 4 | – | – | – | – | – | – | – | – | – |
5e | – | – | – | – | – | – | – | – | – | – |
5f | – | – | – | – | – | – | – | – | – | – |
5g | 10 | – | – | – | – | – | – | – | – | – |
5h | 11 | – | – | – | – | – | – | – | – | – |
5i | 10 | – | – | – | – | – | – | – | – | – |
5j | 6 | – | – | 10 | – | 8 | – | – | – | – |
5k | – | – | – | – | – | – | – | – | – | – |
5l | 9 | – | – | 6 | – | – | – | – | – | – |
5m | 5 | – | – | 8 | – | – | – | – | – | – |
5n | 7 | – | – | – | 5 | – | – | – | – | – |
PC | 28 | 26 | 20 | 28 | 20 | 30 | 20 | 18 | 18 | 20 |