Fig. 6

Apoptotic and necrotic cell death were assessed using Annexin V and Probidium Iodide (PI) staining and analyzed using flow cytometer after 24 h treatment of azetidinone derivatives. a WI-38 cells control (DMSO), b WI-38 cell treated with 500 µg/mL of 6c, c WI-38 cell treated with 500 µg/mL of 6d, d WI-38 cell treated with 500 µg/mL of 6k, and e quantification of apoptotic and necrotic cell death for each drug on WI-38 cells