Skip to main content

Table 1 The IC50 (µg mL−1) of the compounds 1, 2, 3, 5, 6, 7a–d, 8 against breast cancer (MCF-7) cell line

From: Synthesis of some novel 2-(3-cyano -6-(thiophen- 2-yl)-4,4′- bipyridin-2- yloxy)acetohydrazide derivatives: assessment of their cytotoxic activity

Compounds

MCF-7 IC50 (µg)

Dox.

1.6 ± 0.02

1

4 ± 0.18

2

8.2 ± 0.7

3

1.3 ± 0.04

5

28.7 ± 1.4

6

4.7 ± 0.3

7a

3.5 ± 0.2

7b

4.4 ± 0.2

7c

0.6 ± 0.01

7d

2.7 ± 0.04

8

3 ± 0.2

Back to article page

BMC Chemistry

ISSN: 2661-801X

Contact us