Fig. 9

Morphological and nuclear changes of MCF-7, tumor cells after treatment by chemical compounds 3, and 8 compared with reference drug doxorubcin. Compounds stimulate different nuclear changes such as chromatin fragmented and condensation, nuclei condensation, as demonstrated by acridine orange/Ethidium bromide staining at 200×. Yellow arrows indicate live cell, pink arrows indicate early apoptotic Red arrows indicate necrotic and blue arrows indicate late apoptotic cells