Fig. 5

Morphological and nuclear changes of MCF-7, tumor cells after treatment by chemical compounds 3, 5, and 6 compared with reference drug doxorubcin. Compounds induced various nuclear features such as chromatin fragmented and condensation, nuclei condensation, as demonstrated by acridine orange/Ethidium bromide staining at 200 × . Yellow arrows indicate live cell, pink arrows indicate early apoptotic Red arrows indicate necrotic and blue arrows indicate late apoptotic cells