Fig. 3

Nuclear morphological conersions of MCF-7 cells, after treated using chemical compounds 1, 2, and 3 compared with reference drug doxorubicin. Compounds stimulate different nuclear changes such as condensation and fragmentation of chromatin, nuclei condensation, as demonstrated by acridine orange/Ethidium bromide staining at 200×. Yellow arrows indicate live cell, pink arrows indicate early apoptotic Red arrows indicate necrotic and blue arrows indicate late apoptotic cells