Table 3 Comparison of COX-1 and COX-2 molecular docking data
From: gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect
Compound | COX-1 kcal/mol | COX-2 kcal/mol |
|---|---|---|
A1 | − 6.5 | − 6.6 |
A2 | − 7 | − 6.7 |
A3 | − 7 | − 7.7 |
A4 | − 7 | − 7.7 |
A5 | − 7 | − 7.5 |
Ibuprofen | − 7.8 | − 7.7 |