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Table 3 Comparison of COX-1 and COX-2 molecular docking data

From: gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect

Compound COX-1 kcal/mol COX-2 kcal/mol
A1 − 6.5 − 6.6
A2 − 7 − 6.7
A3 − 7 − 7.7
A4 − 7 − 7.7
A5 − 7 − 7.5
Ibuprofen − 7.8 − 7.7