Skip to main content

Table 7 Precision data for the determination of VPS by Method 1

From: Two novel UPLC methods utilizing two different analytical columns and different detection approaches for the simultaneous analysis of velpatasvir and sofosbuvir: application to their co-formulated tablet

Parameters

Column (A)

Column (B)

Concentration (ng/mL)

Concentration (ng/mL)

1.0

3.0

5.0

2.5

5.0

10.0

Intraday

 % Found

96.83

98.30

99.75

94.23

93.28

99.21

97.78

98.77

99.71

92.00

91.55

98.72

94.82

97.66

99.52

93.23

96.26

98.60

 (\( \overline{{\text{x}}} \))

96.48

98.24

99.66

93.15

93.70

98.84

 ± SD

1.51

0.56

0.12

1.12

2.38

0.32

 %RSD

1.5.7

0.57

0.12

1.2

2.54

0.33

 %Error

0.9

0.33

0.07

0.69

1.47

0.19

Inter-day

 % Found

98.24

98.30

99.72

92.97

96.61

99.30

99.44

96.31

100.42

100.22

99.13

100.66

99.44

96.31

100.42

93.72

99.51

99.79

 (\( \overline{{\text{x}}} \))

99.04

96.97

100.19

95.46

98.42

99.92

 ± SD

0.69

1.15

0.40

3.99

1.58

0.69

 %RSD

0.70

1.19

0.40

4.17

1.60

0.69

 %Error

0.40

0.68

0.23

2.41

0.92

0.40

  1. Each result is the average of three separate determinations