|
Studied drug
|
Proposed method
|
Comparison method [11]
|
|---|
|
Amount taken (ng/mL)
|
Amount found (ng/mL)
|
% Found
|
% Found
|
|---|
|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
|---|
|
SFV
|
120.0
|
120.0
|
121.208
|
120.765
|
101.01
|
100.64
|
100.61
|
|
200.0
|
200.0
|
200.205
|
199.979
|
100.10
|
99.99
|
99.71
|
|
280.0
|
280.0
|
279.372
|
279.766
|
99.78
|
99.92
|
99.82
|
|
400.0
|
400.0
|
399.597
|
400.431
|
99.90
|
100.11
|
99.89
|
|
600.0
|
600.0
|
601.597
|
600.989
|
100.27
|
100.16
|
100.06
|
|
Mean
| | | | |
100.21
|
100.16
|
100.02
|
|
± SD
| | | | |
0.48
|
0.28
|
0.354
|
|
t-test
| | | | |
0.72
|
0.72
|
(2.31)*
|
|
F-test
| | | | |
1.86
|
1.57
|
(6.39)*
|
|
VPS
|
30.0
|
30.0
|
29.134
|
30.045
|
97.11
|
100.15
|
96.41
|
|
50.0
|
50.0
|
51.597
|
49.907
|
103.19
|
99.81
|
98.24
|
|
70.0
|
70.0
|
69.821
|
70.056
|
99.74
|
100.08
|
98.10
|
|
100.0
|
100.0
|
100.119
|
99.523
|
100.12
|
99.52
|
99.58
|
|
150.0
|
150.0
|
150.321
|
149.981
|
100.21
|
99.99
|
99.47
|
|
Mean
| | | | |
100.07
|
99.91
|
98.36
|
|
± SD
| | | | |
2.16
|
0.25
|
1.29
|
|
t-test
| | | | |
2.06
|
0.95
|
(2.78)*
|
|
F-test
| | | | |
2.82 (6.39)*
|
0.0009 (0.156)*
| |
- Each result is the average of three separate determinations
- * Figures between parentheses are the tabulated t and F values at P = 0.05 [17]
