Studied drug
|
Proposed method
|
Comparison method [11]
|
---|
Amount taken (ng/mL)
|
Amount found (ng/mL)
|
% Found
|
% Found
|
---|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
---|
VPS
|
1.0
|
2.5
|
1.016
|
2.469
|
101.64
|
98.79
|
101.12
|
2.0
|
3.5
|
1.989
|
3.551
|
99.47
|
101.47
|
102.45
|
3.0
|
5.0
|
2.987
|
4.980
|
99.57
|
99.60
|
99.78
|
4.0
|
7.5
|
3.992
|
7.497
|
99.80
|
99.96
|
101.77
|
5.0
|
10.0
|
5.015
|
10.002
|
100.30
|
100.02
|
99.14
|
Mean
| | | | |
100.16
|
99.97
|
100.85
|
± SD
| | | | |
0.89
|
0.97
|
1.37
|
t-test
| | | | |
0.95
|
1.17
|
(2.31)*
|
F-test
| | | | |
2.39
|
1.99
|
(6.39)*
|
- Each result is the average of three separate determinations
- * Figures between parentheses are the tabulated t and F values at P = 0.05 [17]